"Destroy it!" - Lord of the Rings: Fellowship of the Ring. Elrond shouts it pretty much just after the start of the movie

Also, I know this isn't a film quote, in fact, it's from Halo 2, but it's still a freakin' awesome quote! I will have to censor one word, though. (if you've ever played Halo 2 then you'll know what this quote is about. If you haven't, then search
Sgt. Johnson Regret Regret Regret and it should be the first video. Anyway...
Sergeant Johnson: 'Dear Humanity: we regret being alien ********, we regret coming to Earth and we most definitely regret the core just blew up our raggedy ass fleet!' "Oo-rah!"